Sesamol

Sesamol ufa Mfundo Zachidule

dzina	Sesamol ufa
Zofuna	White powder
Cas	533-31-3
Assay	≥99%
Kutupa	nsoluble m'madzi kapena mowa, sungunuka mu Acetic acid, ethyl ester.
Unyinji wa Molar	138.12 g / mol
Melt Point	62 ku 65 ° C (144 ku 149 ° F; 335 ku 338 K)
Molecular Formula	C7H6O3
Malo otentha	21 mpaka 127 ° C (250 mpaka 261 ° F; 394 mpaka 400 K) pa 5
SMILES	mmHgO1c2ccc (O) cc2OC1

 

Kodi sesamol ndi chiyani?

Sesamol, pamodzi ndi metabolites ake ophatikizika, imagawidwa mu ziwalo zathupi monga chiwindi, ubongo, mapapu komanso impso.

Sesamol ikamilowedwa m'thupi, imateteza ku DNA kuti isawonongeke komanso imathandizira kukonza kwa DNA kuti iwonongere kuwonongeka kwa ma radiation a baada ya radiation.

Chifukwa cha mitundu yosiyanasiyana ya vivo bioactivities, sesamol imagwira ntchito yofunika kwambiri pakuchiza matenda osiyanasiyana. Kafukufuku wina adazindikira kuti sesamol imalepheretsa mapangidwe a cell ya HepG2. Izi zikuthandizira kafukufuku wina yemwe akuwonetsa kuti Sesamol ufa (533-31-3) amawononga kufunikira kwa maselo a khansa.

Nthawi zambiri, maselo ambiri am khansa amafunika kupanikizika kwambiri poyerekeza ndi maselo athanzi kuti akhalebe olimba.

Kafukufuku wina akuwonetsa kuti kulumikizana kwa sesamol ndi DNA mwina kumachitika pang'onopang'ono. Komabe pamenepa, kafukufuku wina akuwonetsa kuti ma cell omwe amamangidwa ndi masamol kumangidwa kwa gawo la S, ndipo izi zimachitika modalira. Umu ndi momwe sesamol imapangitsa kuwonongeka kwa DNA ndikulepheretsa kubwereza kwa DNA.

 

Njira zitatu zopangira sesamole

1.Extraction kuchokera ku mafuta a Sesame

Kuphatikiza kwa Sesamol kuchokera ku Sesame mafuta ndi kosavuta kwambiri mwa njira zitatuzi. Komabe, ndizokwera mtengo. Chifukwa chake njirayi siyabwino pakupanga mafakitale, makamaka chifukwa cha mtengo wokwera wopangira.

 

2.Synt synthesis kuchokera ku piperamine

Ngakhale ndizachuma mwachimodzimodzi pamlingo waukulu wa Sesamol Production, njira yonse ya masamu kuphatikiza kuchokera ku piperamine imagwiranso ntchito popanga kanthu kakang'ono pamene ntchito ya hydrolysis ndi hydrolysis ikugwira ntchito. Zikatero, mapangidwe a pigment chifukwa chogwirizanitsidwa komanso zotsatira zake sizingalephereke.

 

3.Semi yopanga njira yochokera ku jasmonaldehyde

Njira yopanga yochokera ku jasmonaldehyde ndiyo njira yogwiritsidwa ntchito kwambiri posakaniza synthes monga momwe mafakitale akukhudzira. Mchitidwewu umaphatikizapo oxidation ndi hydrolysis ndipo chifukwa cha izi, sesame phenol yoyambira ndi yapamwamba komanso yapamwamba kwambiri.

Njirayi imagwiritsa ntchito makina amitundu yosiyanasiyana komanso yotsika mtengo, yomwe imathandizira kuti magawo azigawa mwachangu. Izi zimachepetsa kuthekera kwa mayankho amtsogolo. Palibe zodabwitsa kuti malonda omaliza (oyera ngati krustalo) ali apamwamba kwambiri pankhani ya mtundu ndi mawonekedwe a sesamol.

 

Tzotsatira zake zazikulu za sesamol

Anti-oxidation kwenikweni

Pokhala chakudya chachilengedwe chokhala ndi katundu wamphamvu wa antioxidant, sesamol itha kugwiritsidwa ntchito popanga nyama yanyama makamaka, nkhumba ndi ng'ombe, imakhala ndi alumali yotalika. Zimalepheretsa kuwonongeka kwa oxidative mu nyama yosungidwa, ndikupangitsa kuti izikhala yabwino popanda kuyambitsa zinthu zomwe zingakhale ndi chiopsezo chaumoyo kwa ogula.

Kuphatikiza apo, kafukufukuyu adapeza kuti kusanjikiza kwapawiri komanso kuphatikiza ndi zinthu zothana ndi oxidation monga sesame phenol kungalepheretse kusintha kwa mtundu wa nyama ya m'mawere ndi nyama yophika, lipid peroxidation ndi volatilization ndi kutaya kwa kubalalitsa, kuti zitheke zotsatira zakusungidwa.

 

 Anti-chotupa

Kafukufuku wotsatira wawonetsa kuthekera kwa sesamol popewa kukula kwa maselo a lukemia mwa anthu. Oxidant wachilengedwe amatipatsa izi mosadalirana. Mwamwayi, mosiyana ndi mankhwala ena othandizira chotupa, sesamol siyipangitsa vuto lililonse pama cell abwinobwino.

 

 Kutsitsa kwaulere mosamala

Ma radicals aulere amatha kuyambitsa machitidwe osiyanasiyana azaumoyo ngati mawonekedwe awo abwinobwino komanso kuperewera koyenera sikumasungika. Kupatula apo, kusasinthasintha kwaulere kungapangitse kuti ukalamba ukhale mwa munthu.

Kuphatikiza apo, sesamol ikhoza kulepheretsa m'badwo wama hydroxyl radicals ndi superoxide anions, potero zimakhudza thupi Mphamvu ya oxidative nkhawa ndi chiwindi chogwira ntchito zimayendetsa bwino.

 

Anasintha kagayidwe kachakudya

Metabolic syndrome imanena za vuto lathanzi lomwe limabwera chifukwa cha zovuta za metabolic monga Obesity, hyperinsulinemia, matenda ashuga ndi hyperlipidemia.

Sesamol imatha kusintha kunenepa kwambiri (kuchuluka kwambiri kwamafuta minofu m'thupi) ndi:

Kuchepetsa kunena kwa gengenic gene

Kulimbikitsa lipolytic jini Ppara mawu

Kudula kufotokozera zamtundu womwe umayambitsa cholesterol m'badwo (Hmgcr ndi Acat2)

Monga sesamin, sesamol imatha kukonza ntchito ya mitochondria m'chiwindi komanso minofu ya adipose, potero imaletsa kunenepa kwambiri.

 

Anti-cheza

Dera lomwe tikukhalamoli limakonda kuyatsidwa ndi ma radiation owopsa, chifukwa cha sayansi komanso kupita patsogolo kwaumisiri. Mwamwayi, malinga ndi kafukufuku wa Yow GG et al kuti akhazikitse kuthekera kwa anti-radiation ya sesamol, ofufuzawo adazindikira kuti panganolo limateteza DNA ndi cell cell yoteteza ku radiation

 

Kumene angagule sesamol ufa wambiri?

Ngati mukufuna Sesamol yaiwisi yaiwisi, Chonde tithandizeni kuti mutilankhule, Ndife ogulitsa Sesamol kwa zaka zingapo, Timapereka zinthu ndi mtengo wapikisano, makasitomala abwino ndi zinthu zabwino,
Ndife osinthasintha pakusintha kwa malamulo kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogola mwachangu pama oda amatitsimikizira kuti mudzasangalala ndi ntchito yathu. Timapezekanso pamafunso amtumiki ndi zidziwitso zothandizira bizinesi yanu.

 

zitsambal ufa Reference

1. Sesamol Yosungidwa 2010-01-14 ku Wayback Machine ku Chemicalland21.com
2. Joo Yeon Kim, Dong Seong Choi ndi Mun Yhung Jung "Antiphoto-oxidative Activity ya Sesamol ku Methylene Blue- ndi Chlorophyll-Sensitized Photo-oxidation ya Mafuta" J. Agric. Chakudya Chem., 51 (11), 3460 -3465, 2003.
3. Osawa, Toshiko. "Sesamol ndi sesaminol monga antioxidants." Makampani Atsopano a Zakudya (1991), 33 (6), 1-5.
4. Wynn, James P .; Kendrick, Andrew; Ratledge, Colin. "Sesamol monga choletsa kukula komanso kagayidwe kake ka lipid mu Mucor circinelloides kudzera pamagetsi a michere." Lipids (1997), 32 (6), 605-610.
5. "Kuyang'anitsitsa Mankhwala a Ayurvedic". Yang'anani pa Mankhwala Othandizira ndi Njira Zina. Bethesda, Maryland: National Center for Complementary and Alternative Medicine (NCCAM), US National Institutes of Health (NIH). 12 (4). Kugwa 2005 - Zima 2006. Zasungidwa kuchokera koyambirira pa 2006-12-09.
6. Li, Jie Jack (2004). Kuphatikizika kwamankhwala osokoneza bongo. Hoboken, NJ: Wiley. ISBN 978-0-471-21480.Mitundu: Natural phenolsPhenol