2021 Maupangiri Ogwiritsa Ntchito Mankhwala Osokoneza Ubwino Ogonana Ochiza Erectile Dysfunction (ED)

 

Mbiri yakukula kwa chithandizoKulephera kwa Erectile (ED)

Kulephera kwa Erectile kwakhala nkhawa kwa amuna kuyambira chiyambi cha mbiri yolembedwa. Chithandizo cha ED chidayamba kale m'zaka za zana lachisanu ndi chitatu, pomwe amuna aku Roma wakale ndi Greece adavala zithumwa za maliseche a tambala ndi mbuzi. Khulupirirani kuti imatha kugwira ntchito ngati aphrodisiac ndikulimbikitsa kugonana. Pofika kumapeto kwa zaka za zana la 18, kuchotsedwa kwa testis ya nkhosa kudabayidwa ngati gwero la testosterone kuti athetse kusowa mphamvu. Mu 1970s, ma implants a penile adadzipangira dzina ngati yankho la kukanika kwa erectile. Nthawi yomweyo, mapampu otulutsira penile anali kutchuka ndipo "chida chofananirana ndi achinyamata" cha Geddings Osbon (kapena YED) chinali kukonza njira yopumira zida za mbolo zomwe tikudziwa mpaka pano. A 1980 adayala maziko osintha zakugonana ndi kafukufuku wa Dr. Giles Brindley. Brindley adalowetsa vasodilator m'mitsempha yake, zomwe zidapangitsa kuti minofu igwire bwino ntchito ndikukhala ndi erection. Zomwe adapeza zidapangitsa kuti afufuze za vasodilator ndi ma alpha-blocking agents ngati chithandizo cha erectile dysfunction. Kupambana kwakukulu kunachitika Kumayambiriro kwa zaka za m'ma 1990, sildenafil idavomerezedwa ngati mankhwala amtima, ndipo zidadziwika kuti amuna omwe amamwa mankhwalawa anali ndi zovuta, zokhalitsa. Izi zidapangitsa kuti pakhale kafukufuku wambiri pa sildenafil ngati mankhwala osokoneza bongo, ndipo Pfizer adawulula Viagra mu 1998. Sildenafil adakhala mankhwala oyamba amkamwa ovomerezeka kuchiza ED. Chithandizo cha vuto la erectile chidasinthidwa ndikupeza sildenafil kapena Viagra. Izi zinatsatiridwa ndi kugwiritsa ntchito tadalafil ndi vardenafil monga ofanana phosphodiesterase-5 mankhwala oletsa kumwa pakamwa pochiza ED mu 2003. Kwa amuna ambiri, moyo sunakhalepo wabwino.

 

Kufufuza momwe zinthu zilili pa Erectile Dysfunction (ED)

Kulephera kwa Erectile (ED) ndichizoloŵezi chachipatala chachimuna, kafukufuku wofufuza adawonetsa kuti ED ikuchulukirachulukira ndi msinkhu: pafupifupi 40% ya amuna amakhudzidwa ali ndi zaka 40 ndipo pafupifupi 70% ya amuna amakhudzidwa ali ndi zaka 70. Kukula kwa ED wathunthu yawonjezeka kuchokera ku 5% ali ndi zaka 40 mpaka 15% ali ndi zaka 70.2 Age anali mtundu wosiyanasiyana womwe umalumikizidwa kwambiri ndi ED. Kuchepa kwa chilakolako chogonana ndikukula. Amuna pagulu lakale kwambiri (50 mpaka 59) anali ndi mwayi wopitilira 3 nthawi zokumana ndi mavuto ndikukhala ndi chilakolako chochepa chogonana poyerekeza ndi amuna 18 mpaka 29. Kukumana ndi zovuta zakugonana kunali kotheka kwambiri pakati pa amuna omwe anali ndi thanzi labwino komanso lamaganizidwe.

M'zaka makumi angapo zapitazi, pakhala kuwonjezeka kwakukulu pakumvetsetsa kwathu kwa ma physiologic omwe amachititsa kuti erectile iwonongeke (ED). Kulephera kwa Erectile (ED) kwakhala mutu wazofalitsa zambiri komanso chidwi pakati pa anthu komanso kuvomereza. Kufanana ndi kuwonjezeka kwa chidziwitso kwakhala kuphulika pamankhwala othandiza.

 

Kodi Erectile Dysfunction (ED) ndi chiyani?

Kulephera kwa Erectile kapena disorde (ED), komwe kumatchedwanso kusowa mphamvu, ndiko kulephera kukhazikitsa ndikukhazikitsa njira yokomera zogonana kapena zochita. Nthawi zambiri magazi akamatuluka mu mbolo amakhala ochepa kapena misempha imavulala. Nthawi zambiri zimayambitsidwa ndi vuto la thanzi, monga: kupsinjika, kutopa, nkhawa ndi zina zambiri Mutha kuyesa kugwiritsa ntchito mankhwala osokoneza bongo, kuthetsa zomwe zimayambitsa, kusintha moyo wanu ndi kuthetsa mavuto amisala ndi chithandizo chamankhwala.

Ngati mukufuna njira zochizira ED yanu, nkhaniyi ikupatsani chidziwitso chothandiza kwa anthu omwe ali ndi vutoli, kapena omwe ali pafupi nawo.

(1) Makina a erectile dysfunction (ED)
Izi zimapangitsa kuti mbolo yanu ikule ndikulimba pamene magazi akudzaza zipinda ziwiri zotchedwa corpora cavernosa, ngati buluni chifukwa imadzazidwa ndi madzi. Zokopa kuchokera kuubongo ndi mitsempha yamaliseche zimayamba. Chilichonse chomwe chimatseka zikhumbozi kapena kuletsa kuthamanga kwa magazi kupita ku mbolo kumatha kuyambitsa ED.

(2) Zizindikiro / Zizindikiro za kuwonongeka kwa erectile (ED)
Mwamuna amadziwika kuti ali ndi ED pomwe izi zikuchitika pafupipafupi:

Zovuta kupeza erection
Vuto lokhala ndi erection
Kuvuta kusunga erection kwa nthawi yayitali yokwanira

Zovuta zina zakugonana ndizokhudzana ndi ED ndipo zimatha kuyambitsa matenda ofanana ndi ED, monga:

Kuthamangira msanga (kutulutsa umuna posachedwa)
Kulephera kukhala ndi vuto pambuyo pakulimbikitsidwa kokwanira
Kuthamangitsidwa mochedwa (pamene kutulutsa umuna kumatenga nthawi yayitali) muvi wolunjika mmwamba
Magulu otsika a testosterone testosterone
Kuchepetsa libido kapena kuyendetsa kugonana
Kulephera kwa minofu ya m'chiuno
Kupweteka kwa mafupa a chiuno, monga mafupa a m'chiuno

Kafukufuku wina wasonyeza kuti amuna omwe ali ndi ED ali pachiwopsezo chachikulu chodwala matenda a mtima, sitiroko kapena kuzungulira kwa miyendo. ED imayambitsanso:

Kudziyang'anira pansi
Kusokonezeka maganizo
Zovuta za mwamunayo ndi mnzake

Lankhulani ndi dokotala ngati muli ndi izi, makamaka ngati akhala kwa miyezi itatu kapena kupitilira apo. Amatha kuthandizira kudziwa ngati zizindikilo zanu zimayambitsidwa ndi vuto lomwe likufuna chithandizo. Cholinga chake ndi kukonza kapena kupititsa patsogolo ntchito ya erectile, kuthandizira kuzungulira kwa magazi ndikuthandizira moyo wamunthu

(3) Kusiyana pakati pa ED ndi kuyendetsa bwino zogonana
Amuna atha kukhala ndi mitundu ingapo yamavuto kuphatikiza kuyendetsa kosagonana komanso mavuto okomedwa. Koma ED imanena makamaka za zovuta kupeza kapena kusunga erection. Mutha kukhala ndi chilakolako chogonana, koma thupi lomwe silingayankhe. Nthawi zambiri pamakhala chifukwa chakuthupi chavutolo.

Nchiyani chimayambitsa kukanika kwa erectile (ED)?

Amuna amatenga nawo gawo pakukonzekera kudzera muubongo, mahomoni, malingaliro, misempha, minofu ndi mitsempha yamagazi. Iliyonse la mavutowa lingayambitse kapena kuthandizira ku ED. Ndi ukalamba, kuchuluka kwa amuna omwe ali ndi zizindikilo za ED kudzawonjezeka ndikuwonjezeka kwa moyo, koma ukalamba sudzatsogolera ku ED. ED imatha kuchiritsidwa msinkhu uliwonse.

Moyo unayambitsa ED
Kusankha moyo kumatha kuchititsa ED, kusuta, kumwa mowa kwambiri, komanso kugwiritsa ntchito mankhwala osokoneza bongo kumatha kusokoneza kuyendetsedwa kwa magazi ndikubweretsa kusokonekera kwa erectile. Kulemera kwambiri komanso kuchita masewera olimbitsa thupi pang'ono kumathandizanso kuti erectile iwonongeke. Amuna omwe amachita masewera olimbitsa thupi nthawi zonse amakhala ndi chiopsezo chotsika cha kutha kwa erectile.

Psychological idapangitsa ED
Kukhala ndi malingaliro abwino kumatha kudzutsa ubongo, ngati muli ndi nkhawa, thanzi lamisala monga kukhumudwa kapena nkhawa, ubongo wanu umatha kukhala ndi vuto lopanga kulumikizana kwa mitsempha ndikutulutsa mahomoni omwe amachititsa kuti mukhale ndi erection. Chifukwa chake zovuta zamaganizidwe zitha kukhala gawo lothandizira pakukanika kwa erectile.

Matenda Aakulu adayambitsa ED
Kulumikizana pakati pa matenda osachiritsika ndi ED kumakhala kochititsa chidwi kwambiri shuga. Amuna omwe ali ndi matenda ashuga amakhala ndi mwayi wowirikiza kawiri kapena katatu kukhala ndi vuto la erectile. Matenda aliwonse omwe amakhudza momwe magazi amayendera mthupi lanu amatha kupita ku ED. Izi zikuphatikiza matenda a mtima, atherosclerosis (kuuma kwa mitsempha), matenda a impso, ndi multiple sclerosis.

Mankhwala adayambitsa ED

Mankhwala ambiri amatha kuyambitsa matenda osokoneza bongo, kuphatikizapo kuthamanga kwa magazi, mankhwala osokoneza bongo, antihistamines, mankhwala a acid reflux, mankhwala opweteka a opioid. ndi zotontholetsa. Lankhulani ndi dokotala wanu ngati mukuganiza kuti mankhwala akuchipatala kapena owonjezera pa intaneti atha kuyambitsa mavuto a erectile. Koma musasiye kumwa mankhwala musanakambirane ndi dokotala.

Opaleshoni idapangitsa ED
Opaleshoni kapena radiation ya khansa ya prostate, khansa ya chikhodzodzo, kapena kukulitsa kwa prostate (BPH) nthawi zina imatha kuwononga mitsempha ndi mitsempha yamagazi pafupi ndi mbolo. Ngati kuwonongeka kwa mitsempha sikukhalitsa, mudzafunika chithandizo kuti mukhazikike. Koma nthawi zina opaleshoni imayambitsa ED kwakanthawi komwe kumakhala bwino patadutsa miyezi 6 mpaka 18.

 

Momwe mungadziwire ngati mukuleza mtima ndi ED?

Nthawi zambiri, ngati mukuwoneka kuti mulibe chidwi kapena chikhumbo chogonana, kulephera kudzutsidwa, kugonana kopweteka, mutha kukhala mukukumana ndi vuto la erectile. Nthawi zina, kapena kwakanthawi, zovuta zakugonana sizitanthauza kukanika kwa erectile.

 

Momwe mungachitire ndi kuwonongeka kwa erectile (ED)?

Kulephera kwa Erectile (ED) kumatha kukhudza amuna azaka zosiyanasiyana, koma sizingakhudze moyo wake. Nkhaniyi itha kukuthandizani kupeza chithandizo choyenera ndikuthandizira kuthandizira kukhala ndi moyo wogonana ndikukwaniritsa magwiridwe antchito anu a erectile, kukupangitsani kuti mumverenso ku umunthu wanu wakale.

Mankhwala
Kwa amuna ambiri, nthawi zambiri amaganiza kuti azimwa mankhwala akumwa a erectile dysfunction (ED) chithandizo choyamba, kuti athandizire kupeza erection. Amunawa opititsa patsogolo mankhwala opatsirana pogonana (PDE5 inhibitors) akuphatikizapo tadalafil (Cialis), sildenafil (Viagra), vardenafil (Levitra, Staxyn) ndi avanafil (Stendra), kudzera pakupititsa patsogolo ntchito zogonana pochepetsa minofu yosalala ndikuchulukitsa magazi kulowa mu mbolo. Simuyenera kumwa chilichonse mwa mankhwalawa kuti muchiritse kuwonongeka kwa erectile (ED) ngati mukumwa nitrate a matenda amtima. Mankhwala a testosterone (TRT) amathanso kulimbikitsidwa ngati mulibe testosterone. Alprostadil (Caverject, Edex, MUSE) ndi mankhwala ena ovomerezeka ndi FDA omwe atha kugwiritsidwa ntchito pochiza kuwonongeka kwa erectile (ED). Itha kuperekedwa m'njira ziwiri: monga penile suppository kapena ngati kudzipiritsa jekeseni m'munsi kapena mbali ya mbolo. Jekeseni ya Penile ndiye mtundu wabwino kwambiri wamankhwala a ED kwa amuna omwe sangamwe mankhwala pakamwa.

Mawotchi Aids
Ngati mankhwala sakugwira ntchito kapena oyenera, zida zopumira ndi zida za penile ndi zina zothandizira zingathandizenso abambo kukwaniritsa kapena kukhalabe ndi erection. Iyenso imavomerezedwa kuti igwiritsidwe ntchito mwa akazi, ingokhalani okwera mtengo kwambiri. Ma Dilator amatha kuthandiza amayi omwe amachepa kumaliseche. Zipangizo monga ma vibrator zitha kukhala zothandiza kuthandizira kukonza chisangalalo chogonana komanso pachimake.

Njira zamankhwala
Pali mankhwala ena osagwiritsidwa ntchito moyenera komanso "zowonjezera zakudya" zomwe zimati zimachiza kuwonongeka kwa erectile, monga: Panax ginseng supplements, ginkgo, madzi a khangaza, ndi yohimbe zowonjezera zina. Koma si mankhwala onse "achilengedwe" kapena zowonjezera zomwe zili zotetezeka. Choyamba musanagwiritse ntchito chowonjezera chilichonse, kuti muwonetsetse kuti ali ndi chitetezo chokwanira cha ED.

Psychotherapy
Kuthandizidwa ndi mlangizi wophunzitsidwa bwino kungakuthandizeni kuthana ndi zovuta zakugonana zakale, nkhawa, kukhumudwa, stree, komanso mawonekedwe oyipa amthupi. Amatha kukuthandizani komanso mnzanu kuti mugwirizanenso mwamalingaliro, zomwe zingathandizenso ED.

Limbikitsani Opaleshoni
Kwa amuna ambiri, opareshoni iyenera kukhala njira yomaliza, kudzera pakuchita opaleshoni ya minyewa kukonza zina mwazovuta za ED. Nthawi yochira imasiyanasiyana, koma kuchuluka kwake kumakhala kokwanira.

 

Mankhwala othandiza kwambiri ogonana a 5 othandiza kuthana ndi vuto la erectile (ED) padziko lapansi?

Malipoti ambiri achikale akuwonetsa kuti mankhwala otsatirawa okhudzana ndi kugonana a 4 ndi othandiza kwambiri kuthandiza amuna kuthana ndi vuto la erectile dysfunction (ED).

(1)Tadalafil
Tadalafil ndi m'kalasi la mankhwala amkamwa otchedwa phosphodiesterase (PDE) inhibitors, ogulitsidwa pansi pa dzina la Cialis ndi Adcirca, amagwiritsidwa ntchito kuthana ndi vuto la erectile dysfunction (ED) ndi zizindikilo za benign prostatic hypertrophy (BPH, prostate wokulitsa). Tadalafil imagwira ntchito poonjezera kuthamanga kwa magazi kupita ku mbolo kuti zithandizire abambo kupeza ndikumangirira. Nthawi zina, amagwiritsidwanso ntchito kuthana ndi kuthamanga kwa magazi (PAH) (kuthamanga kwa magazi m'mitsempha yamagazi yomwe imapereka mapapo).

Malipoti ambiri achikale akuwonetsa kuti Tadalafil (Cialis) ndi mankhwala okhalitsa kwambiri a PDE5 a ED, amatha mpaka 36 ~ 72hours.Pali njira ziwiri ngati zingafunike kutenga tadalafil kuti athetse vuto la erectile, tadalafil sichimakhudzidwa ndi chakudya, itha kutengedwa ngati tsiku lililonse kapena maziko ofunikira. Ngati tadalafil imatenga tsiku ndi tsiku, itha kuyesa kugonana nthawi iliyonse pakati pa mlingo wanu, musatenge tadalafil mobwerezabwereza kamodzi patsiku, kuchuluka kwa tadalafil ndi 2.5 mg mpaka 5 mg pakamwa kamodzi patsiku. Ngati tadalafil imatenga ngati ikufunika, nthawi zambiri osachepera mphindi 30 musanachite zogonana, kuchuluka kwa tadalafil ndi 5 mg mpaka 20 mg kumadalira poyankha Cialis (tadalafil) osati kangapo kamodzi pa maola 24 aliwonse. Mphamvu ya Tadalafil pakukhudzana ndi kugonana imatha mpaka maola 36 ~ 72. Mukamamwa tadalafil nthawi zonse ndikusowa mlingo, imwani mukamakumbukira. Ngati pafupi ndi nthawi yotsatira mlingo, dumpha mlingo womwe wasowa, imwani mlingo wotsatira nthawi yanthawi zonse. Osachulukitsa mlingo kuti mupeze. Tadalafil imafunika kusungira kutentha kwapakati kutali ndi kuwala ndi chinyezi, siyingasunge mchimbudzi, ndikusunga mankhwala onse kutali ndi ana ndi ziweto, imangotengedwa ndi achikulire azaka 18 kapena kupitilira apo.

Kuphatikiza apo, mankhwala onse atha kubweretsa zoopsa komanso phindu. Ngakhale tadalafil ikugwira ntchito, mutha kukhala ndi zovuta zina za tadalafil, kuphatikizapo: kupweteka mutu, kupweteka m'mimba, kupweteka kwa msana, kupweteka kwa minofu, mphuno yodzaza, kuthamanga, kapena chizungulire, ndi zina zotero. kapena wamankhwala mwachangu. Kawirikawiri, ngati masomphenya akusintha kapena kutaya mwadzidzidzi (kuphatikizapo khungu losatha, m'maso amodzi kapena m'maso onse)), kutalika kwa nthawi yayitali kwa maola 4 kapena kupitilira apo, kuchepa kwadzidzidzi kapena kutaya kumva, nthawi zina ndikulira m'makutu ndi chizungulire. (zotupa, kuyabwa / kutupa, chizungulire, kupuma movutikira ndi zina) ndi zovuta zina zoyipa, siyani kumwa tadalafil ndikupita kuchipatala nthawi yomweyo.

Pakadali pano, mapiritsi / kapisozi wamlomo wa Tadalafil (Cialis) amatha kulumikizana ndi mankhwala, mankhwala, mavitamini, komanso zakudya zowonjezera kapena zitsamba. Pofuna kupewa kuyanjana ndi Tadalafil, muyenera kudziwa momwe tadalafil ingagwirizane ndi china chake chomwe mumatenga, ndikulankhula ndi dokotala kapena wamankhwala. Musayambe, kuimitsa, kapena kusintha mlingo wa mankhwala aliwonse popanda kuvomerezedwa ndi dokotala. Nthawi zonse lolani dokotala ndi wamankhwala za mankhwala anu onse apano.

(2)Vardenafil Hydrochloride

Vardenafil, yomwe imadziwikanso ndi dzina loti Levitra kapena Staxyn, ndi mankhwala othandiza omwe amachiza kukanika kwa amuna, imabwera ngati piritsi komanso kuphulika mwachangu (kusungunuka mkamwa ndikumeza popanda madzi) piritsi loti atenge pakamwa. Monga mankhwala ena a PDE5 a ED, vardenafil imagwira ntchito pakukulitsa magazi kulowa mbolo. Njira yogwiritsira ntchito Vardenafil yomwe ndi nitric oxide imayambitsa enzyme guanylate cyclase yomwe imapangitsa kuchuluka kwa cyclic guanosine monophosphate (cGMP) m'maselo osalala a corpus cavernosum. CGMP imayambitsa kupumula kwa minofu, kumawonjezera magazi kulowa mu mbolo, zomwe zimapangitsa kuti pakhale erection. Ntchito ya Vardenafil ndiyofanana ndi sildenafil kapena Viagra, koma Viagra imatha pakati pa 2 ndi 4 maola, pomwe Vardenafil (Levitra) imakhala maola 4. Komabe, kugwiritsa ntchito vardenafil sikuyenera kwa amayi, ndipo zovuta za vardenafil panthawi yapakati kapena poyamwitsa akazi sizidziwika.

Malipoti ambiri achikale akuwonetsa kuti vardenafil ndi mankhwala osankhika oyamba othandiza kuthana ndi vuto la erectile, imagwira ntchito mwachangu pang'ono kuposa Viagra (sildenafil) ndi Cialis (tadalafil), itha kugwira ntchito bwino ngati vardenafil itatengedwa mphindi 30 mpaka 60 musanachite zogonana. Vardenafil imatha kumwedwa kapena wopanda chakudya. Koma kumwa mowa sikulangizidwa, chifukwa kumachepetsa mwayi wokhala ndi erection. Mowa amathanso kuwonjezera ngozi zakubwera. Komabe, Vardenafil imagwira ntchito mwachangu ikagwidwa pamimba yopanda kanthu. Mlingo woyambira wa vardenafil ndi 10 mg, kutengera mphamvu ndi kulolerana kwa mlingowo utha kukulitsidwa mpaka 20 mg kapena kutsika mpaka 5 mg, ndipo mulingo woyenera kwambiri ndi 20 mg. Vardenafil sayenera kumwa mobwerezabwereza patsiku pamlingo uliwonse, youma manja anu musanagwiritse ntchito vardenafil, chotsani mlingowo phukusi la vardenafil nthawi yomweyo, ikani vardenafil piritsi lilime lanu ndikulola kuti lisungunuke kwathunthu. Musaphwanye kapena kugawaniza piritsi, vardenafil sayenera kumwedwa ndi madzi, imafunikira malo otentha kutali ndi chinyezi ndi kutentha.

Musatenge vardenafil ndi mankhwala ofanana palimodzi, monga avanafil (Stendra), sildenafil (Viagra), kapena tadalafil (Cialis), itha kukhala ndi mwayi wothandizana ndi mankhwala ena kapena chakudya chomwe mukumwa. Pakadali pano, pewani kugwiritsa ntchito zipatso za manyumwa, kumwa mowa ndi fodya, kumakulitsa zovuta zina za vardenafil. Muyenera kulankhula ndi dokotala kapena wamankhwala mukamamwa piritsi la vardenafi ndi mankhwalawa, kungakuthandizeni kupewa kuyanjana ndi vardenafi.

(3)Avanafil
Avanafil (Stendra) ndi mankhwala ena a PDE5, omwe amagwiritsidwa ntchito pochiza matenda osokoneza bongo a erectile (ED). Avanafil imagwira ntchito ngati mankhwala ena m'kalasimo powonjezera magazi kupita ku mbolo, popanda mawonekedwe achibadwa, ndi mankhwala otetezeka a ED. Mosiyana ndi Tadalafil (Cialis) ndi Sildenafil (Viagra), zikuwonetsa kusankha kwakukulu kwa PDE5 kuposa PDE6 kuposa onse sildenafil ndi vardenafil, koma osasankha kuposa tadalafil. Avanafil itha kugwiritsidwa ntchito payokha kapena ndi mankhwala ena, osadziwika ngati avanafil ndiotetezeka komanso yothandiza kwa ana.

Malipoti ambiri osonyeza kuti avanafil ndi mankhwala atsopano a FDA ovomerezeka pamsika, imagwira ntchito mwachangu kwambiri kuposa mankhwala ena m'kalasi lomwelo, amangogwira mphindi 15. Avanafil imatha kutengedwa ndi wopanda kapena wopanda chakudya, ndikololedwa kwambiri, imatha mpaka maola asanu ndi limodzi. Mitengo ya zotsatira zoyipa za avanafil ndi ena mwamankhwala otsika kwambiri a PDE5 inhibitors. Ndipo, avanafil ngati mankhwala odziwika ndi dzina, mtengo wa avanafi umakhala wokwera mtengo kuposa mankhwala ena opititsa patsogolo kugonana. Amawonekera makamaka m'mapiritsi am'kamwa pochiza nkhani yamphongo ya ED, pali mphamvu zitatu za mapiritsi a avanafil: 50 mg, 100 mg ndi 200 mg. Kwa amuna omwe amatenga 50mg avanafil mlingo, amafunika kutenga mphindi 30 musanagonane; Kwa abambo omwe amamwa mankhwala avanafil mu 100mg ndi 200mg, zimangotenga mphindi 15 musanagonane, ndipo musatenge avanafil kangapo patsiku. Avanafil amafunikira sitolo kutentha, kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa), komanso komwe ana sangakwanitse.

Kuphatikiza apo, avanafil imakhalanso ndi machitidwe a pharmacodynamic, muyenera kukambirana ndi dokotala kapena wamankhwala ngati mukufuna kumwa mankhwala ena osalembetsedwa, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba, omwe angathandize kupewa kuyanjana kwa avanafi ndi zovuta za avanafi.

(4)Dapoxetine Hydrochloride

Dapoxetine hydrochloride (hcl) ndichosankha posankha serotonin reuptake inhibitor (SSRI), idavomerezedwa koyambirira kuti athandize amuna omwe ali ndi kutaya msanga (PE). Dapoxetine imagwira ntchito poletsa wotumiza serotonin ndikuchulukitsa kuchitapo kanthu kwa serotonin pama pre-and postynaptic receptors, ndi ufa wonyezimira komanso wosasungunuka ndi madzi, imatha kulowetsedwa mthupi, ndikulekerera bwino, ndi mankhwala apakamwa a Erectile Dysfunction and Ejaculatory Disorders . Mlingo woyambira wa dapoxetine ndi piritsi limodzi la 30mg, tengani piritsi la dapoxetine 1 ~ 3 maola musanachite zogonana, akhoza kuchulukitsidwa kukhala dapoxetine 60 mg pakatha milungu 4 yamasabata a 12, kufunikira kokwanira kwa ddapoxetine kamodzi kamodzi kwamaola 24. Zotsatira zoyipa za dapoxetine zimaphatikizapo chizungulire, kupweteka mutu ndi mseru. Mukamamwa mankhwala ena, chonde funsani dokotala kapena wamankhwala kuti muwone ngati angatenge ndi dapoxetine, angakuthandizeni kupewa kuyanjana kwa dapoxetine ndi mankhwala ena.

 

(5) Sildenafil
Sildenafil ndi mankhwala oyamba am'kamwa kuti FDA ivomerezedwe koyambira koyamba kwa erectile dysfunction (ED), ndi choletsa chodziwika bwino cha PDE5. Sildenafil imagwira ntchito poonjezera kuthamanga kwa magazi kupita ku mbolo mwa kumasula mitsempha yamagazi ndi minofu yosalala kuti muthandize abambo kupeza ndikumangirira. Komanso, Sildenafil itha kugwiritsidwa ntchito mwa abambo ndi amai pochiza matenda oopsa am'mapapo, imagwira ntchito pa enzyme ya PDE5 m'mapapu kuti imasule mitsempha yamagazi, izi zimawonjezera magazi m'mapapu ndikuchepetsa ntchito yamtima. Sildenafil ndiyotchuka kwambiri kuposa mankhwala ofanana nawo, okhala ndi mitundu ya generic komanso mtundu. Viagra & Revatio ingagulitsidwe pamsika pansi pa dzina la Sildenafil, itha kutengedwa pakamwa kapena jekeseni mumtsempha, mitundu ya sildenafil imabwera ngati piritsi ndi ufa kuti ziyimitsidwe. Kuyamba kumakhala mkati mwa mphindi 20 ndipo kumatha pafupifupi maola awiri.

Kwa odwala ambiri kuti agwiritse ntchito sildenafil pochiza matenda ophera erectile (ED), mlingo woyenera wa sildenafil ndi 50mg, ngati pakufunika, tengani sildenafil osachepera mphindi 30 musanachite zachiwerewere, koma osapitilira maola 4, ola la 1 isanakhale yothandiza kwambiri, chitani osatenga kangapo patsiku. Kutengera kulimbika ndi kulolerana, sildenafil dose itha kukulitsidwa mpaka mulingo woyenera kwambiri wa sildenafil 100 mg kapena kutsika mpaka sildenafil 25 mg, itha kumwedwa kapena wopanda chakudya. Koma, chakudya chamafuta ambiri chomwe chimaphatikizidwa ndi sildenafil chingachedwetse momwe mankhwalawo amayambira kugwira ntchito mwachangu.

 

 

Sildenafil motsutsana Tadalafil VS Vardenafil VS Avanafil Ndi iti yomwe ili yabwino kwambiri?

Sildenafil (Viagra), Tadalafil (Cialis), Vardenafil (Levitra) ndi Avanafil (Stendra) ndiwo mankhwala opatsirana pogonana opatsirana pogonana a Erectile Dysfunction (ED), amagwira ntchito ndikuwonjezera magazi kulowa mbolo, ndi a mankhwala omwe amadziwika kuti PDE5 inhibitors.Sildenafil, Tadalafil, Vardenafil ndi Avanafil amagwira ntchito mofananamo, mankhwala aliwonse ali ndi mawonekedwe osiyana pang'ono, motero mankhwala aliwonse amasiyana pang'ono, koma amagwira ntchito bwino ndipo amayambitsa zovuta zochepa .

 

Sildenafil vs Tadalafil (Viagra vs Cialis)
Tadalafil ndi sildenafil ndi awiriwa omwe ali ndi phosphodiesterase 5 inhibitors omwe amagwiritsidwa ntchito pochiza matenda ophera erectile (ED), onsewo amangogwira ntchito pokhapokha ngati amuna agonana, mofananamo komanso chitetezo, zitha kulimbikitsa kwambiri chidaliro cha amuna. Komabe, amuna ambiri amakonda Tadalafil kuposa sildenafil, chifukwa imatenga nthawi yayitali, imagwira ntchito mwachangu komanso zotsatira zoyipa, tadalafil silingakhudzidwe ndi chakudya chimodzimodzi ndi sildenafil. Ndipo mosiyana, amuna ena amakonda sildenafil atayesa tadalafil osagwirizana nawo.

Sildenafil vs Vardenafil (Viagra vs Levitra)
Vardenafil ndi sildenafil nawonso ndi PDE-5 inhibitors omwe akuwonetsa kuti amathandizidwa ndi amuna erectile dysfunction (ED). Mwapangidwe, vardenafil ndiyofanana ndi sildenafil, imakhala yamphamvu kwambiri komanso yosankha kuposa sildenafil poletsa phosphodiesterase-5. Pochiza ED, vardenafil effect ndi yofanana ndi sildenafil, onse amatha maola anayi kapena asanu ndi limodzi. Phindu lokhalo la vardenafil ku sildenafil, sililetsa phosphodiesterase-6 kusintha mawonekedwe amtundu, ndipo sildenafil nthawi zina limakhala ndi zotsatira zoyipa. Mankhwala onsewa amatha kumwa, koma Vardenafil samakhudzidwa kwambiri ndi chakudya kapena mowa. Kuphatikiza apo, ena amati amaletsa vardenafil imathandiza kwambiri odwala matenda ashuga kuposa mankhwala ena osagwira ntchito.

Sildenafil vs Avanafil (Viagra vs Stendra)
Sildenafil ndi Avanafil ndizofanana mofananira, ali ndi mankhwala omwewo a PDE5 inhibitors, onse amalekerera bwino. A. Sildenafil ndi Avanafil ndimankhwala ochepera a ED, koma Avanafil imagwira ntchito mwachangu kwambiri, wokhala ndi theka lotalikirapo, imagwira ntchito mkati mwa mphindi 5 mutatha kumwa. Avanafil imakhala chithandizo chofulumira kwambiri chogwiritsa ntchito erectile pamsika. Mtengo wa avanafil ndiwokwera kwambiri kuposa ma PDE15 inhibitors ena, koma sildenafil imawoneka yotchuka kwambiri, mwina mtengo wa sildenafil ndi wotsika kwambiri ndipo umawonekera koyambirira pamsika.

Tadalafil vs Avanafil (Cialis vs Stendra)
Tadalafil ndi avanafil zimagwiranso ntchito chimodzimodzi, kugwiritsidwa ntchito pochiza matenda osokoneza bongo a erectile (ED), zimakhala ndi zovuta zambiri komanso zoyanjana. Avanafil idavomerezedwa ndi US FDA ku 2012 ndipo idakhala PDE5I yachinayi pamsika, yololera bwino, theka la moyo wa avanafil limangokhala ndi gawo limodzi mwa magawo atatu a tadalafil. Imayamba mwachangu komanso imakhala yayifupi kuposa tadalafil

 

Tadalafil vs Vardenafil (Cialis vs Levitra)

Tadalafil (Cialis) ndi Vardenafil (Levitra) ndi ovomerezeka ndi FDA kuti athetse vuto la erectile dysfunction (ED), amachokera mgulu lomwelo la mankhwala, Tadalafil ndi mankhwala tsiku lililonse omwe amathandizira kutulutsa prostate, Vardenafil imagwiritsidwa ntchito ngati mankhwala za kuwonongeka kwa erectile (ED). Komabe, tadalafil imatha kuchita zinthu mwachangu kuposa Vardenafil ndipo imatenga nthawi yayitali ndi zotsatira zake, Tadalafil ndi Vardenafil ali ndi zovuta zoyanjana komanso kulumikizana, mankhwala onsewa atha kugwiritsidwa ntchito kapena wopanda chakudya chofunikira asanayambe kugonana, kuyamwa kwa Vardenafil kokha kumatha kukhudzidwa ndi kudya mafuta, kuyamwa kwa Tadalafil sikungakhudzidwe ndi chakudya.

	Vardenafil	Tadalafil
Kalasi ya mankhwala	Phosphodiesterase-5 (PDE5) choletsa	Phosphodiesterase-5 (PDE5) choletsa
kachirombo	Zolemba & generic	Zolemba & generic
fomu	Piritsi lapakamwa	Piritsi lapakamwa
Mlingo woyenera	5 mpaka 20 mg pakufunika musanachite zogonana kamodzi tsiku lililonse monga adalangizira dokotala	5 mpaka 20 mg momwe amafunira musanachite zogonana kapena 2.5 mpaka 5 mg kamodzi tsiku lililonse malinga ndi malangizo a dokotala
Imakhala nthawi	osachepera mphindi 60 dzanja lisanachitike.	Mphindi 30 musanagonane
Zotsatira zoyipa	yothina kapena yothamanga m'mphuno, kupweteka kwa mutu, kuthamanga, kutuluka m'mimba, kudzimbidwa, komanso kupweteka msana	yothina kapena yothamanga m'mphuno, kupweteka kwa mutu, kuthamanga, kutuluka m'mimba, kudzimbidwa, komanso kupweteka msana
Chithandizo chamankhwala	kutengedwa ngati pakufunika, osavomerezeka monga kugwiritsidwa ntchito kwatsiku ndi tsiku	kutengedwa ngati pakufunika, kugwiritsa ntchito tsiku ndi tsiku kungakhale koyenera kwa anthu ena.

Sildenafil vs Tadalafil vs Vardenafil vs Avanafil
Sildenafil, Tadalafil, Vardenafil ndi Avanafil sichidzachiza kuwonongeka kwa erectile (ED), koma atha kukupumutsirani kuzizindikiro zake. Thupi la aliyense limayankha kusiyana pakulimbikitsa mankhwala ogonana, zotsatirapo zake zimasiyanasiyana malinga ndi munthu, njira yokhayo yodziwira kuti ndi mankhwala ati omwe angakuthandizeni mwina poyeserera. Kapena mumagwira ntchito molunjika ndi dokotala kapena wamankhwala, kuti muwone zotsatirapo zake ndikusankha mankhwala omwe angakuthandizeni pakusankha kwanu kwa erectile dysfunction (ED).

Phosphodiesterase-5 inhibitors a Erectile Dysfunction (ED)
mankhwala	Siligalafil	Tadalafil	Vardenafil	Avanafil
Brand	Viagra	Cialis	Levitra	Stendra
Mtundu wa generic	inde	inde	inde	Ayi
fomu	piritsi yamlomo kapena kuyimitsidwa kwamadzi	piritsi yamlomo	piritsi yamlomo	piritsi yamlomo
Mlingo wamba	25 mg, 50 mg, 100 mg	2.5 mg, 5 mg, 10 mg, 20 mg	5 mg, 10 mg, 20 mg	50 mg, 100 mg, 200 mg
Nthawi: Nthawi	2 ~ 3hours	mpaka maola 36	hours 4 ~ 5	hours 6 ~ 12
Kuyamba (mphindi)	30 ~ 60	15 ~ 30	30 ~ 60	15-30
Kuyamwa komwe kumachitika ndi chakudya	Inde (chakudya chamafuta ambiri)	Ayi	Inde (chakudya chamafuta ambiri)	Ayi
Mlingo	pakufunika	tsiku lililonse kapena sabata	pakufunika	pakufunika
yosungirako	Pa 25 ° C (77 ° F)	Pa 25 ° C (77 ° F)	Pa 25 ° C (77 ° F)	Kutentha kwapakati, pakati pa 68 ° F mpaka 77 ° F (20 ° C mpaka 25 ° C)

 

Zokumana Nazo pa Reddit

Nazi zina mayankho ochokera kwa Redditors atayesa mankhwala opititsa patsogolo kugonana kuti athandize amuna ED:

-alireza
“PDE5 inhibitors samakupangitsani kukhala owopsa ndipo samapangitsanso kuti zizimveka zokha, zimathandizira kuti magazi aziyenda bwino chifukwa chake mukalimbikitsidwa, mawonekedwe ake ndiabwino kwambiri. Chifukwa chake ngati MUKUFUNA zolaula kuti musangalatse sangasinthe izi. Pankhani ya PE ndikuganiza kuti zoletsa za PDE5 zitha kukhala zomveka kuti aliyense azitha kuwonjezera magazi. Zina mwazinthu zomwe tatchulazi zitha kugwira ntchito potengera izi, ngakhale zomwe ndimakonda ndi tadalafil "

-Chizindikiro chimodzi
”Ndakhala ndikugwiritsa ntchito tadalafil pafupifupi zaka zitatu. ndipo tsopano ndili ndi zaka 3. Ndidadula piritsi la 63mg tadalafil m'kati (pafupifupi 20mg) ndipo ndimamwa kamodzi tsiku lililonse la 5. Ndimasankhidwa nthawi iliyonse ndikafuna ndipo ndimamva bwino. Ndiyenera kunena kuti ndikukhulupirira ndi mtima wonse kuti kugwiritsa ntchito izi kumandipangitsa kukhala wamantha kwambiri kuposa kale lonse "

--Kumpoto chakum'mawaGuyinTX
"Ndimamwa tadalafil 20 mg m'mawa uliwonse ndi mavitamini anga. Imakhala m'dongosolo lanu mpaka maola 36, ​​ndi theka la maola 1. Kutenga tadalafil tsiku lililonse mosaganizira zachiwerewere zimandichitira bwino. Ndilibe zovuta, ndipo ndikulakalaka kupita nthawi iliyonse. Izi zimathandiza ndi mphindi zokha. Mukapeza mlingo woyenera wa tadalafil, ndikulangizani kuti muzimwa nthawi zonse tsiku lililonse tsiku lililonse ... ”

--Jim_jonson
"Tadalafil imandithandiza kuti ndikhale ndi erection yolimba, yodalirika. Ndimawona kuti kukhala wolimba kumachepetsa kukhudzika komanso kuda nkhawa ndikapangidwe kanga, zomwe zimapangitsa kuti ndikhale wautali kwambiri esp. pophunzitsa mokhulupirika. ”

--TheLoneDeranger76
”Ndakhala nazo zonse ziwiri ndipo ndimakonda tadalafil kuposa sildenafil citrate. Makamaka ngati mukufuna kuchotsa MDMA, tadalafil imagwirabe ntchito. Sildenafil citrate amandipatsanso asidi Reflux. Tadalafil ikuwoneka kuti ikugwiranso ntchito bwino. Zosintha bwino komanso zazitali ”

--Key_Mwend_9315
"Tadalafil ndiyabwino kuposa vardenafil, zotsatira zake zimatha mpaka maola a 36 omwe amadziwikanso kuti" mapiritsi a sabata "koma vardenafil ndi tadalafil zotsatira zimangokhala maola 5 komanso osagwira ntchito ngati mumadya chakudya chamafuta ambiri koma tadalafil imagwira bwino ntchito popanda vuto lililonse . ”

—Kumva Nkhandwe
”Ndine 58 ndipo ndakhala ndikugwiritsa ntchito vardenafi 20 mg kwa zaka zingapo. Zimandithandizira ine ndi mkazi wopanda zovuta zina. ”

--JadmZimz4evr
”Ndili ndi IPAH. Ndimatenga tadalafil 40mg ndi Opsumit (macitentan) 10mg. Combo ija yandigwirira ntchito bwino kwa zaka 5 zapitazi. Kugonekedwa pang'ono apa ndi apo, koma kwathunthu, kwabwino kuposa ma 5yrs omwe ndidakhala osadziwika. Katswiri wanga anandiuza kuti sildenafil siyolimba ngati tadalafil, koma banja lokonda kugwiritsa ntchito mankhwala osokoneza bongo. The generic amatchedwa Alyq. Inshuwaransi ina imakusungani ku Sildenafil chifukwa ndiotsika mtengo. Mwina kulandira mankhwalawa kungathandize kuchepetsa mtengo wa sildenafil. ”

—CraftyLiving6
”Ndine wazaka 33yrs. Ine ndi mkazi wanga tili achangu kwambiri pamoyo wathu wogonana. koma miyezi ingapo yapitayi ndikuvutika kuti ndikhale ndi erection, ngakhale malingaliro anga ndi thupi langa akuti inde, mbolo yanga ikuti ayi. Chifukwa chake ndimagula sildenafil ndikuganiza kuti itha kundithandiza ndipo ndinadabwa kuti zimandithandizadi. Zinali zovuta kwambiri. Ndikumva kuti iphulika. ”

 

Zochitika Zogawana pa Quora

Nawo ndemanga kuchokera ku Quora mutayesa mankhwala opititsa patsogolo kugonana kuti athandize amuna ED:

-Andres Bruce
"Tadalafil imagawana ntchito yofananira ndi chitetezo ndi Sildenafil Citrate ndipo imathandizira kwambiri kutsimikizika kwa ogonana. Kuphatikiza apo, odwala ndi omwe amathandizana nawo amapita ku tadalafil kupita ku sildenafil. Chifukwa chake, tadalafil ikhoza kukhala chisankho chabwino kuposa chithandizo cha ED "

-Anthony Skilton
”Piritsi yatsopano yopititsira patsogolo ED yafika pamsika m'zaka zaposachedwa ndipo ndi Stendra (Avanafil). Nayi tione kuyerekezera kwa Avanafil vs Sildenafil Citrate. Mankhwala onsewa amatha kuthandizira kuthana ndi vuto lanu la ED. Komabe, Avanafil ndiye wopambana, popeza amakhala ndi nthawi yayitali yogwira ntchito komanso zoyipa zochepa. Kuphatikiza apo, Sildenafil Citrate ndiokwera mtengo kwambiri ndipo sikhala nthawi yayitali. Izi zitha kukupangitsani ndalama zambiri pamapeto pake. Pazonse, Avanafil ndiye wopambana kuposa onsewa ”

-Bob Smith
”Tadalafil (Cialis) Tsiku lililonse, yomwe imadziwika kuti mapiritsi a sabata, ndi imodzi mwanjira zothandiza kwambiri kwa odwala omwe ali ndi vuto la erectile. Kugwira ntchito moyenera komanso kwakanthawi kwa mankhwalawo kumapangitsa kuti pakhale kukhazikika kokhazikika komanso kwanthawi yayitali, kuthandizira kukodzera msanga ndi zovuta zina. Tadalafil tsiku lililonse ndi imodzi mwazogulitsa zogulitsa kwambiri padziko lonse lapansi masiku ano ”

-Dennis Rodrigue
”Kulephera kwa Erectile ndikutulutsa msanga msanga ndizovuta ziwiri zomwe zimapezeka mwa amuna. Dapoxetine 60mg imagwira gawo lofunikira pakusungitsa ED ndi PE panthawi yamaubwenzi ”

--Amit Panigrahi
"Ngakhale mankhwala osokoneza bongo monga Sildenafil (viagra), Tadalafil (Cialis) amandithandizira vuto la kuwonongeka kwa erectile (ED), samathandizanso kukulitsa nthawi yogonana. Pazinthu zoterezi (kutanthauza kuchedwa kutulutsa umuna, mwachitsanzo nthawi yowonjezera yogonana) mankhwala ena a Dapoxetin akugwiritsidwa ntchito. Mutha kupeza zopangidwa ndi mankhwala okhala ndi dapoxetin kuti mukulitse nthawi yogonana. Zina mwazopezekanso ngati sildenafil + dapoxetin, Tadalafil + dapoxetin… ”

-Dr.Stam Poupalos
”Kulephera kwa Erectile ndi chizindikiro osati mkhalidwe chifukwa kumatha kukhala ndi zifukwa zingapo. Psychological ED imatha kuganiziridwa kuti imachiritsidwa nthawi zina pomwe thupi la ED, chifukwa cha kuwonongeka kwa mitsempha kapena mavuto azizungulire, limatha kuchiritsidwa ngati silichiritsidwa. Mulimonsemo thandizo lilipo lomwe lingathe kuthana ndi vutoli. ”

- Anatero Bob Nicholson
”Kunena zowona, zilibe kanthu kuti uli kuti. Chithandizo chothandiza kwambiri ku ED ndi PDE-5 inhibitor (Sildenafil Citrate, Tadalafil, Vardenafil, ndi ofanana nawo) ... ”

--Dana Shultze
”Sildenafil imagwiritsidwa ntchito ndi iwo omwe ali ndi vuto la Erectile Dysfunction mwa amuna. Sildenafil komanso Viagra. Sildenafil ndi mapiritsi ofatsa omwe amathandizanso pochiza matenda oopsa a m'mapapo mwanga (PAH). Sildenafil imagwira ntchito kupumula minofu mu penile ndikulimbikitsa magazi kutuluka. Kugwiritsa ntchito mankhwala kwathunthu uku kumathandiza amuna kukwaniritsa ndi kukhala ndi erection kwa nthawi yayitali ”

— José Saravia
"Zikuwoneka kuti sildenafil imagwirira ntchito omanga thupi, chifukwa chake ndikuti molekyulu ya nitric oxide ndichinthu chofunikira kwambiri cha sildenafil ndipo zowonjezera zowonjezera zomanga thupi zimamangidwa mozungulira molekyulu yomweyi ndipo zimagulitsidwa kuti zigwiritsidwe ntchito ngati vasodilator asanalowe kulimbitsa thupi. Komanso omanga thupi ambiri, amatenga Sildenafil pamodzi ndi anabolic steroids asanafike ku masewera olimbitsa thupi. ”

Kodi Gulani mankhwala odalirika ogonana pa intaneti?

Kugula mankhwala pa intaneti ndikosavuta komanso mwachangu kuposa kale. Ngati mukufuna kugula mankhwala opatsirana pogonana pochiza nkhani yamwamuna wa ED kudzera muma pulatifomu osiyanasiyana pa intaneti. kulibwino ugule kwa wogulitsa yemwe ali ndi mbiri yabwino yogulitsa mankhwala otetezedwa komanso othandiza ogonana. Kutengera zomwe takumana nazo ndi malingaliro abwino ochokera kwa ogula, cmoapi.com ndiogulitsa mankhwala osokoneza bongo odziwika bwino omwe amapititsa patsogolo mankhwala osokoneza bongo pamitengo yapikisano.

 

Zolemba Zosintha